In the first phase of our clinical study we evaluated the results after giving the preparation to patients. Patient's consent was essential in line with adequate information provision regarding the advantages and disadvantages of the product administration.
Penoxal 50 mg was given 3x1 for 3 months, usually repeatedly with a pause of 3 months. We checked HB, HT, thrombocytes, leucocytes and differential counts, liver tests, HD/ LD cholesterol, urea, blood glucose, s- amylase and BP.
In our study, 45 patients were assigned to 5 groups:
Female patients with a higher risk of breast cancer - 7 patients
Patients with a dysplastic nevus syndrome (FAMMM) - 15 patients
Polyps and other risk factors in patients with a high risk of colon Ca - 3 patients
Patients with severe family medical history - 7 patients
Patients with a confirmed tumour (3 with breast Ca, 3 with melanoma Clark I, 4 with melanoma Clark III, 1 with
melanoma Clark IV, 4 with confirmed colon tumour), out of these cases, one was inoperable.
M.D. Jan Hynek
Centre for Clinical Oncology and Mammology
Palackého ul.201, Trutnov